Brian Hoyer gets the start on the road against an angry Niners defense. Good luck with that.
2
Bears
at Lions
The Bears need to win to get in; Matt Stafford needs to throw to reach milestones. Can you say "pick-six"?
3
Broncos
vs. Chiefs
Denver is going after a higher seed, at the expense of the hapless Chiefs.
4
Seahawks
vs. Rams
The roll Seattle is on, you don't want to get in their way.
5
Chargers
vs. Raiders
Expectations are low for Terrell Pryor in his first NFL start--unless you're starting the Chargers defense, that is.
TIER 2
6
Giants
vs. Eagles
Michael Vick returns, just in time to face the Giants in a game Big Blue must win. Nice timing.
7
Bengals
vs. Ravens
The Bengals are motivated, their defense is underrated, and Joe Flacco is on the road. That's an intriguing combination.
8
Patriots
vs. Dolphins
Speaking of underrated defenses, the Patriots have one of their own--and they still need to win.
9
Browns
at Steelers
Pittsburgh is playing out the string, which could mean resting the banged-up Ben Roethlisberger.
10
Bills
vs. Jets
Hey, everybody, Mark Sanchez is back!
11
Texans
at Colts
As good as Andrew Luck has been, he's been prone to the pick. And Houston's still playing for a seed, too.
12
Vikings
vs. Packers
A good pass rush, a bad Green Bay offensive line, a loud Metrodome, a playoff spot on the line, and Adrian Peterson playing keepaway from the Packers' offense.
13
Jets
at Bills
The Vegas line on interceptions in Sanchez v. Fitzpatrick is 6.5. We'll take the over.
14
Cardinals
at 49ers
Arizona's defense is actually pretty good. And they'll likely have plenty of kickoff return opportunities.
15
Titans
vs. Jaguars
Less an endorsement of the Titans than an indictment of the Jaguars.
TIER 3
16
Saints
vs. Panthers
Down the stretch they've been playing like the opportunistic, fantasy-friendly defense from their Super Bowl season.
17
Rams
at Seahawks
Don't underestimate Jeff Fisher's defense.
18
Ravens
at Bengals
This is not the Ravens defense of old, but they still know their way around a turnover.
19
Panthers
at Saints
It's a pretty good pass defense, and Drew Brees hasn't been nearly as precise as in past seasons.
20
Steelers
vs. Browns
Cleveland may be down to their third-string quarterback. Oh, if this were a different iteration of the Steel Curtain.
21
Colts
vs. Texans
Indy's defense has played well of late, and now there's something at stake.
22
Redskins
vs. Cowboys
Isn't it about time for Tony Romo to turn into... well, the Tony Romo fantasy defenses know and love?
23
Falcons
vs. Buccaneers
The Bucs have been playing giveaway recently, but it may be the backup Falcons' defense for much of this contest.
24
Packers
at Vikings
Still no Charles Woodson, but there's enough defensive talent here to make things tough for Christian Ponder.
25
Cowboys
at Redskins
RG3 has taken excellent care of the ball all season long, but maybe Dallas turns up the heat in prime time.
TIER 4
26
Jaguars
at Titans
Jake Locker is definitely pick-prone.
27
Dolphins
at Patriots
Tough to see Tom Brady making mistakes at home in a game with some meaning.
28
Raiders
at Chargers
San Diego is all kinds of banged up, leaving Philip Rivers to force the issue. Maybe Oakland can take advantage.
29
Eagles
at Giants
Philly would love nothing better than to end Eli's season with a spate of turnovers.
30
Lions
vs. Bears
You'd think Detroit's d-line against the Bears' o-line would be a better matchup, but it's unlikely to turn out that way.
31
Buccaneers
at Falcons
About the only thing working in Tampa Bay's favor is that Atlanta will likely rest its regulars at some point.
32
Chiefs
at Broncos
There's a reason one team has two wins and the other has Peyton Manning playing for a playoff seed.