Chester Rogers - WR - Indianapolis Colts
Indianapolis Colts WR Chester Rogers attracted a total of 22 targets in Week 4 and Week 5 combined, tied for ninth most in the league over that stretch.
Huddle Up: It ties him with Tyler Boyd, Keke Coutee and Adam Thielen. While his recent activity is based almost exclusively on the fact the Colts don't have T.Y. Hilton and Jack Doyle available due to injury and lack any semblance of a running game, it doesn't change the fact he appears to be Andrew Luck's favorite receiver at the moment. Facing a New York Jets' defense missing slot corner Buster Skrine in Week 6, Rogers could be a high-upside WR3 play in seasonal and DFS formats.
Todd Gurley - RB - Los Angeles Rams
Los Angeles Rams RB Todd Gurley has amassed an NFL-high 32 carries inside the 20 through five games. Gurley led the league in red zone carries last season with 62.
Huddle Up: For some more perspective on how impressive that number is, New Orleans RB Alvin Kamara ranks second with 20, while New England Patriots RB Sony Michel is third with 17. No other running back has half of Gurley's total. The number is not only a reflection on the Rams' trust in Gurley, but also how proficient the offense has been in general. It's not like owners needed another reason to keep Gurley in their lineups, but he'll be in the running for overall RB1 honors this week against the Denver Broncos.
Carlos Hyde - RB - Cleveland Browns
Cleveland Browns RB Carlos Hyde has nine carries inside the 5 through five games, trailing only the Los Angeles Rams' Todd Gurley (10) for the most in the league.
Huddle Up: While the threat of losing carries to Nick Chubb and Duke Johnson is very real at some point, Hyde is still handling most of the action and being trusted to handle the most important carries. He is one of 10 running backs who has handled all of his team's carries inside the 5. His volume and goal-line role should keep him firmly in the fantasy RB2 discussion for the foreseeable future.
Deshaun Watson - QB - Houston Texans
Houston Texans QB Deshaun Watson (chest) is listed as questionable to face the Buffalo Bills in Week 6 but is expected to play, according to a source.
Huddle Up: There is always a chance he could aggravate the injury, but Watson's dual-threat ability is worth that risk.
O.J. Howard - TE - Tampa Bay Buccaneers
Tampa Bay Buccaneers TE O.J. Howard (knee) is listed as questionable but is expected to play against the Atlanta Falcons in Week 6, according to a source.
Huddle Up: Howard is a matchup nightmare, but he is still searching for consistency. However, his big-play ability from the tight end spot makes him a great streaming option in what could be a high-scoring affair with Atlanta.
Jamison Crowder - WR - Washington Redskins
Washington Redskins WR Jamison Crowder (ankle) is expected to play in the Week 6 game against the Carolina Panthers.
Huddle Up: Crowder and Chris Thompson are not expected to play, and the Redskins have a couple of other receivers dealing with injuries. Shockingly, Jordan Reed might be the healthiest and safest target in the passing game against the Panthers.
Chris Thompson - RB - Washington Redskins
Washington Redskins RB Chris Thompson (ribs, knee) is listed as questionable to face the Carolina Panthers in Week 6, but he is not expected to play, according to a source.
Huddle Up: With Thompson out, Adrian Peterson should see plenty of touches against Carolina. Peterson has been dealing with injuries of his own, but he is expected to play and has RB2 potential.
Isaiah Crowell - RB - New York Jets
New York Jets RB Isaiah Crowell (ankle) is listed as questionable to face the Indianapolis Colts in Week 6, but he is expected to play, according to a source.
Huddle Up: Crowell exploded for 219 yards in Week 5 after three rough games in a row, and while the Colts haven't been great at stopping the run, it is tough to trust a player as inconsistent as Crowell as more than a flex option.
DeAndre Hopkins - WR - Houston Texans
Houston Texans WR DeAndre Hopkins is expected to be covered mainly by Buffalo Bills CB Tre'Davious White in Week 6, and in his last three games, White has held Minnesota Vikings WR Stefon Diggs, Green Bay Packers WR Davante Adams, and Tennessee Titans WR Corey Davis to an average of only five catches for less than 50 yards.
Huddle Up: White is quickly pushing to be considered a shutdown corner, but Hopkins is in the conversation for best receiver in the league. He remains a must-start option this weekend.
Robby Anderson - WR - New York Jets
New York Jets WR Robby Anderson faces the Indianapolis Colts in Week 6, and the Colts are one of two teams that hasn't a completion of 40 or more yards this season.
Huddle Up: Anderson piled up 123 yards and two touchdowns on just three catches in Week 5, but he could find it tough to connect on any big plays against the Colts. Of the Jets receivers, an underneath target like Quincy Enunwa could be the better fantasy option
Dalvin Cook - RB - Minnesota Vikings
Minnesota Vikings RB Dalvin Cook (hamstring) is expected to play against the Arizona Cardinals in Week 6, but he is likely to be limited to 20-25 plays, according to Ben Goessling of the Minneapolis Star Tribune.
Huddle Up: Cook has been dealing with injuries all year, and it's tough to consider him anything more than a risky flex option in Week 6 while stuck on a snap count.
Dak Prescott - QB - Dallas Cowboys
Dallas Cowboys QB Dak Prescott's passer rating dropped from 104.9 in his rookie season to 86.6 last year, and his passer rating sits at 81.4 after five games this season.
Huddle Up: Prescott received a pass for last year's struggles because of the suspension to Ezekiel Elliott, and while you can place some of the blame on his receivers this season, the trend is still discouraging. Even in two-quarterback formats, you can probably find a better option.
Aaron Rodgers - QB - Green Bay Packers
Green Bay Packers QB Aaron Rodgers faces the San Francisco 49ers at home on Monday Night Football in Week 6, and Rodgers is 5-1 with 16 touchdowns and two interceptions when playing at home on Monday Night Football.
Huddle Up: Rodgers threw for 442 yards and three scores in Week 5, and given the state of San Francisco's secondary, another spectacular performance could be on tap Monday night.
Patrick Mahomes - QB - Kansas City Chiefs
Kansas City Chiefs QB Patrick Mahomes faces the New England Patriots in Week 6, and the last eight quarterbacks to face the Patriots with fewer than 10 career starts under their belts have gone a combined 0-8 with six touchdowns and eight interceptions.
Huddle Up: Bill Belichick knows how to make life tough on rookie quarterbacks, but unless you happen to have two elite quarterbacks on your roster, you can't bench Mahomes in Week 6. The Kansas City offense looks too good right now.
Cameron Meredith - WR - New Orleans Saints
New Orleans Saints WR Cameron Meredith (knee) said 'every week has been an improvement' as he returns from knee surgery, and he is just trying to make the most of the opportunities when they arise.
Huddle Up: Meredith saw a season-high in catches, targets and yards against the Washington Redskins in Week 5 with Ted Ginn out of action, and his best could be yet to come as he continues his recovery. He's someone to keep an eye on if you need help at receiver.
David Njoku - TE - Cleveland Browns
Cleveland Browns TE David Njoku will likely see more targets against the Los Angeles Chargers in Week 6 as a result of the injuries to the wide receiving corps, according to Tony Grossi of ESPNCleveland.com.
Huddle Up: Njoku's usage has already been on the rise since Baker Mayfield has taken over as the starter, and he has 11 catches on 18 targets over the last two games. He's still a TE2 in redraft leagues, but he's an intriguing DFS play against the Chargers.
Greg Olsen - TE - Carolina Panthers
Carolina Panthers TE Greg Olsen (foot) is expected to play in Week 6 against the Washington Redskins, and the plan is for him to be in the starting lineup, a source said Saturday, Oct. 13.
Huddle Up: Olsen hasn't had any setbacks with his foot injury and he reportedly had a good week of practice. He's a risky fantasy play, as he returned from a foot injury last season and he aggravated the injury rather quickly. Wait to see him make it through a full game without any setbacks before trusting him again.
George Kittle - TE - San Francisco 49ers
San Francisco 49ers TE George Kittle (knee) was listed as a limited participant for the third straight day Saturday, Oct. 13, and he is listed as questionable for the Week 6 game against the Green Bay Packers on Monday, Oct. 15.
Huddle Up: Kittle is a solid TE1, serving as the security blanket for C.J. Beathard, especially with wide receiver corps banged up and Matt Breida likely to be a game-time decision. However, Kittle has his risk, too, as he was unable to put in a full practice all week. Start him at your own risk on Monday.
Marquise Goodwin - WR - San Francisco 49ers
San Francisco 49ers WR Marquise Goodwin (hamstring, quadriceps) practiced in full for a third straight day Saturday, Oct. 13 and he has been removed from the injury report ahead of the Week 6 game against the Green Bay Packers on Monday, Oct. 15.
Huddle Up: Goodwin could potentially lead the receivers corps in targets, as the unit is rather banged up at the moment. Pierre Garcon is a question mark, Trent Taylor is doubtful and Dante Pettis is out. Goodwin has some WR5 potential in fantasy leagues of 12 or more teams.
Pierre Garcon - WR - San Francisco 49ers
San Francisco 49ers WR Pierre Garcon (shoulder, knee) was a limited participant in practice Saturday, Oct. 13 and he is listed as questionable for Week 6 against the Green Bay Packers on Monday, Oct. 15.
Huddle Up: Garcon might be able to play, and there is opportunity for more work with Trent Taylor (back) doubtful to play and Dante Pettis (knee) ruled out. However, he is still only worth a look as a WR5 in the very deepest of fantasy leagues at this point.