Austin Ekeler - RB - Los Angeles Chargers
Los Angeles Chargers RB Austin Ekeler rushed for 66 yards and one touchdown on 17 carries against the Detroit Lions in Week 2. He also caught six passes for 67 yards during the game.
Huddle Up: Ekeler has been a big part of the offense for the Chargers over the first two weeks and has posted four touchdowns during that span. He will continue to receive plenty of touches while Melvin Gordon is still holding out and should be a No. 2 running back in leagues.
Philip Rivers - QB - Los Angeles Chargers
Los Angeles Chargers QB Philip Rivers went 21-for-36 for 293 yards, zero touchdowns and one interception against the Detroit Lions in Week 2. He also rushed for 12 yards on one carry.
Huddle Up: Rivers has thrown for at least 290 yards in each of the first two games but was held without a touchdown this week. He will face the Houston Texans in Week 3 and can be a low-end No. 1 quarterback in leagues.
Cody Latimer - WR - New York Giants
New York Giants WR Cody Latimer (concussion) suffered a concussion during the Week 2 game and has been ruled out.
Huddle Up: Latimer will need to go through the concussion protocol before he is able to play again. Fantasy players probably should avoid all Giants receivers until Sterling Shepard and Golden Tate return.
James Conner - RB - Pittsburgh Steelers
Pittsburgh Steelers RB James Conner (knee) suffered a knee injury during the Week 2 game and is considered questionable to return.
Huddle Up: Fantasy players should know more about Conner's status in the next day or two. Jaylen Samuels would take over the starting role if Conner misses time and would be at least a flex option.
Trey Burton - TE - Chicago Bears
Chicago Bears TE Trey Burton (groin) is officially active for the team's Week 2 game.
Huddle Up: It is not known if Burton will be limited during the game, which makes him a risky option. He could be a low-end No. 1 tight end in deeper leagues but is not a must-start option.
Ben Roethlisberger - QB - Pittsburgh Steelers
Pittsburgh Steelers QB Ben Roethlisberger (elbow) suffered a right elbow injury during the Week 2 game and is considered questionable to return.
Huddle Up: Fantasy players will need to keep an eye on the situation to see if Roethlisberger will be able to return. Mason Rudolph will take over the starting job if Roethlisberger misses any time but likely can be avoided in fantasy leagues.
David Johnson - RB - Arizona Cardinals
Updating a previous report, Arizona Cardinals RB David Johnson (wrist) was able to return to the Week 2 game after missing some time because of a wrist injury.
Huddle Up: Johnson is a factor in the running and passing game and should be a weekly starting option in all fantasy leagues.
Vernon Davis - TE - Washington Redskins
Washington Redskins TE Vernon Davis (eye) suffered an eye injury during the Week 2 game and is considered questionable to return.
Huddle Up: Davis has been filling in for Jordan Reed at tight end but now both are injured. Reed should be a starting option once he returns.
Vance McDonald - TE - Pittsburgh Steelers
Pittsburgh Steelers TE Vance McDonald (head) was evaluated for a possible concussion during the Week 2 game but he cleared the concussion protocol and returned to the game.
Huddle Up: McDonald has been a solid option in the passing game for the Steelers and can be a low-end No. 1 tight end in fantasy leagues if healthy.
David Johnson - RB - Arizona Cardinals
Arizona Cardinals RB David Johnson (wrist) suffered a wrist injury during the Week 2 game and is considered questionable to return.
Huddle Up: Fantasy players should monitor the situation to see if Johnson will be able to return to the game. Chase Edmonds would take over as the starter if Johnson misses any time and could be at least a flex option.
Kenyan Drake - RB - Miami Dolphins
Miami Dolphins RB Kenyan Drake has been the subject of trade talks with other teams this week.
Huddle Up: Drake was held to only 12 yards last week and will continue to split time with Kalen Ballage as long as he remains with the Dolphins. He probably is only a flex option at this point, but his fantasy value could increase if he is traded.
Cody Latimer - WR - New York Giants
New York Giants WR Cody Latimer (calf) is officially active for the team's Week 2 game.
Huddle Up: Latimer may be the top receiver for the Giants this week but should not be a starting option for fantasy players.
Joe Mixon - RB - Cincinnati Bengals
Cincinnati Bengals RB Joe Mixon (ankle) is officially active for the team's Week 2 game.
Huddle Up: Mixon could receive a few less carries because of the injury but likely will receive most of the work at running back. He can still be a starting running back in all fantasy leagues.
Mike Williams - WR - Los Angeles Chargers
Los Angeles Chargers WR Mike Williams (knee) is officially active for the team's Week 2 game.
Huddle Up: Williams is expected to be limited to only red zone snaps, which hurts his fantasy value. Fantasy players probably should look for other options and keep Williams on the bench.
Mark Andrews - TE - Baltimore Ravens
Baltimore Ravens TE Mark Andrews (foot) is officially active for the team's Week 2 game.
Huddle Up: Andrews played well in Week 1 and likely will receive a solid amount of targets against the Arizona Cardinals. He can be a low-end No. 1 tight end in deeper leagues.
Mark Ingram - RB - Baltimore Ravens
Baltimore Ravens RB Mark Ingram (shoulder) is officially active for the team's Week 2 game.
Huddle Up: Ingram should receive his normal workload this week despite the injury and is a fine No. 2 running back in fantasy leagues.
Marquise Brown - WR - Baltimore Ravens
Baltimore Ravens WR Marquise Brown (hip) is officially active for the team's Week 2 game.
Huddle Up: Brown was one of the breakout fantasy players last week and has become a big part of the Ravens passing game because of his speed. He can be considered a No. 3 receiver or flex option in fantasy leagues this week.
Nick Foles - QB - Jacksonville Jaguars
Jacksonville Jaguars QB Nick Foles (clavicle) had a plate and screws utilized during surgery to repair his broken left clavicle and it was a clean, straight-forward break, according to a source. He will undergo multiple scans in the coming weeks to monitor its progress and could resume practicing before Week 9's game against the Houston Texans, if all goes well. Foles hopes to return to action in Week 11 following the team's bye.
Huddle Up: Gardner Minshew will serve as the Jaguars' starting quarterback in Foles' absence but should not be starting option in any fantasy format, despite turning in a decent relief performance in the regular-season opener.
Sam Darnold - QB - New York Jets
New York Jets QB Sam Darnold (illness) is expected to be sidelined for three to seven weeks as he recovers from mononucleosis. For now, he has been quarantined away from the team.
Huddle Up: Trevor Siemian will be the Jets' starting quarterback in Darnold's stead but he has little fantasy value outside of deeper two-quarterback leagues. Expect the team to rely more heavily on RB Le'Veon Bell during this stretch, while the stock of WRs Robby Anderson and Jamison Crowder will plummet.
Antonio Brown - WR - Oakland Raiders
Updating previous reports, New England Patriots WR Antonio Brown will be active for Week 2's game against the Miami Dolphins.
Huddle Up: Brown has only had a few days to become accustomed to a complicated offense, so expectations should be somewhat tempered for his first game in a New England uniform. However, he's too talented to remain on anyone's fantasy bench this week.