Darren Sproles - RB - Philadelphia Eagles
Philadelphia Eagles RB Darren Sproles' role in the offense will change based on the matchups, according to head coach Doug Pederson. 'So I don't go into it putting a number on it,' Pederson said. 'Just kind of keep it more situational with him.'
Huddle Up: Sproles led the backfield in touches in Week 2 and looks like the safest option in the Philadelphia backfield. Don't expect him to run the ball 20 times a game, but he should be a serviceable flex play in PPR formats in Week 3 against a tough Giants defense.
Jacoby Brissett - QB - Indianapolis Colts
Indianapolis Colts QB Jacoby Brissett said he is tackling even more of the playbook heading into the Week 3 meeting with the Cleveland Browns, and offensive coordinator Rob Chudzinski said he will gradually open up the offense as Brissett becomes more comfortable.
Huddle Up: Brissett doesn't need to be rostered, but he already looked better than Scott Tolzien and should help T.Y. Hilton and Jack Doyle maintain a bit of their fantasy value while Andrew Luck is sidelined.
Andy Dalton - QB - Cincinnati Bengals
Cincinnati Bengals QB Andy Dalton and new offensive coordinator Bill Lazor are not yet at the point where they are speaking the same 'language,' according to Lazor. 'The challenge here right now is making things come out of my mouth real smooth,' Lazor said. 'I can't have any errors.'
Huddle Up: Dalton and the entire Cincinnati offense have been a mess through the first two games. You can give him a couple more weeks to turn things around before sending him to the waiver wire, but he shouldn't be starting in any format against the Packers in Week 3.
Terrance Williams - WR - Dallas Cowboys
Dallas Cowboys WR Terrance Williams (ankle) is listed as questionable for the team's Week 3 game.
Huddle Up: Williams has recorded 10 catches and 85 yards in the first two games and will continue to start opposite Dez Bryant. Owners in most leagues probably will be able to find better options, but Williams could be a possible flex option in deeper leagues.
Carson Palmer - QB - Arizona Cardinals
Arizona Cardinals QB Carson Palmer (non-injury) fully participated in practice Saturday, Sept. 23, and is not on the injury report for Week 3.
Huddle Up: Palmer has thrown for 600 yards, two touchdowns and four interceptions over the first two games of the season and will be without at least one of his receivers. Owners in all leagues should be able to find better options to use and can avoid Palmer.
John Brown - WR - Arizona Cardinals
Arizona Cardinals WR John Brown (quadriceps) did not participate in practice Saturday, Sept. 23, and has been ruled out for Week 3.
Huddle Up: Jaron Brown and JJ Nelson will have bigger roles in the passing game with Brown sidelined. Owners in most leagues can consider Nelson and Jaron Brown a No. 3 receiver or a flex option.
Dede Westbrook - WR - Jacksonville Jaguars
Jacksonville Jaguars WR Dede Westbrook (core) is a candidate to be activated from the Reserve/Injured list later in the season, in the opinion of ESPN.com's Michael DiRocco.
Huddle Up: Westbrook will not return until the middle of the season at the earliest but has a chance to have a solid role in the passing game when he does return. Owners should monitor the situation and could add him to their lineups when he is activated from the Reserve/Injured list.
Austin Seferian-Jenkins - TE - New York Jets
New York Jets TE Austin Seferian-Jenkins could receive a bigger role in the offense in Week 3 if TE Will Tye (illness) is not able to play.
Huddle Up: The Jets probably would want to ease Seferian-Jenkins into the offense since he missed the first two games of the season, but he could receive some targets this week. Owners should avoid Seferian-Jenkins this week, but he could have some fantasy value later in the season.
Jay Ajayi - RB - Miami Dolphins
Miami Dolphins RB Jay Ajayi (knee) missed two practices this week with a knee injury but told reporters he was 'feeling good' despite being listed as questionable on the official Week 3 injury report.
Huddle Up: Ajayi logged 28 carries and 30 total touches in Week 2. The fact he was able to get a full practice and Friday bodes well for him being able to handle a full workload against the New York Jets. Given the competition and Miami's desire to keep Ajayi around all season, don't be surprised if head coach Adam Gase works in Damien Williams and Kenyan Drake a bit more this week than he did in Week 2. Owners should still consider Ajayi a surefire RB1 this week, however.
Terrance Williams - WR - Dallas Cowboys
Dallas Cowboys WR Terrance Williams (ankle) was added to the injury report after not practicing Friday, Sept. 22.
Huddle Up: Regardless of his availability for Week 3's contest against the Arizona Cardinals, Williams should be nowhere near your fantasy starting lineups. He is arguably the Cowboys' fifth-best option in the passing game right now, behind Dez Bryant, Cole Beasley, Jason Witten and Ezekiel Elliott.
DeAndre Hopkins - WR - Houston Texans
Houston Texans WR DeAndre Hopkins has been facing double-teams all season because 'everyone in the league knows we're going to throw the ball to Hopkins,' head coach Bill O'Brien said.
Huddle Up: Hopkins has had trouble breaking loose for big plays, but with 29 targets and 14 receptions through two games, he can still be deployed as a WR2 against the Patriots in Week 3.
Dez Bryant - WR - Dallas Cowboys
Dallas Cowboys WR Dez Bryant has nine catches on 25 targets through two games, and he said while that level of efficiency is 'not acceptable,' he believes the connection between he and QB Dak Prescott will start clicking.
Huddle Up: To be fair, Bryant has faced some tough matchups to open the year, and he draws another one in Week 3 against Patrick Peterson and the Cardinals. He is a boom-or-bust WR2.
Jordan Matthews - WR - Buffalo Bills
Buffalo Bills head coach Sean McDermott said he is happy with WR Jordan Matthews, WR Zay Jones and the rest of the receiving corps.
Huddle Up: Through two games, Matthews is leading the team in receiving with just 91 yards. The Bills are a run-first team to the extreme, and none of Buffalo's receivers are worth starting in Week 3 against the stingy secondary of the Denver Broncos.
Los Angeles Chargers WR Mike Williams (back) is improving every practice but not yet facing contact, head coach Anthony Lynn said Friday, Sept. 22. 'Mike's getting better every single day,' Lynn said. 'He's running full speed, changing direction.'
Huddle Up: Williams has the size to make an immediate impact in the red zone, so continue to stash him if you can afford to give up the roster spot. If he's available in your league, your window to grab him could close in the next week or two.
Melvin Gordon - RB - Los Angeles Chargers
Los Angeles Chargers RB Melvin Gordon (knee) is expected to play against the Kansas City Chiefs in Week 3, head coach Anthony Lynn said Friday, Sept. 22.
Huddle Up: Gordon hasn't had much running room this year, but his work in the passing game and lack of competition for snaps has allowed him to remain an effective fantasy option. As long as he suits up, he should be in your lineup despite the tough matchup.
Ezekiel Elliott - RB - Dallas Cowboys
Dallas Cowboys RB Ezekiel Elliott has been cleared to play in the next two games after the U.S. Court of Appeals for the 5th District set a Oct. 2 court date for the case involving his six-game suspension.
Huddle Up: Elliott was limited to eight yards against the Denver Broncos last week and will be facing an Arizona Cardinals rush defense that ranks in the top-10 in the NFL. Elliott should have more success in Week 3 and can be a No. 1 or No. 2 fantasy running back for owners this week.
Tyler Kroft - TE - Cincinnati Bengals
Cincinnati Bengals TE Tyler Kroft is expected to see an increase in targets in Week 3 against the Green Bay Packers with TE Tyler Eifert (back, knee) ruled out.
Huddle Up: Kroft isn't a terribly attractive fantasy play, although he could be worth a look in the deepest of leagues for his work in the red zone if you need an emergency replacement for Eifert. Kroft might be a nice salary saver in DFS play, too.
Case Keenum - QB - Minnesota Vikings
Minnesota Vikings QB Case Keenum will be the starter again in Week 3 against the Tampa Bay Buccaneers with QB Sam Bradford (knee) on the shelf.
Huddle Up: Keenum being under center means a decrease in fantasy appeal for Stefon Diggs, Kyle Rudolph, Adam Thielen, etc. Diggs and Thielen should be treated as WR3 or WR4 options, while Rudolph is still a red zone threat and a solid low-end TE1. The Buccaneers DST will be a popular fantasy option against the backup QB.
Sam Bradford - QB - Minnesota Vikings
Updating a previous report, Minnesota Vikings QB Sam Bradford (knee) is out for Week 3 against the Tampa Bay Buccaneers and he is seeking a second opinion on his ailing knee.
Huddle Up: It's uncertain when Bradford will be able to return to game action, so it will be Case Keenum under center again this Sunday. That news immediately means a downgrade to the fantasy value of Stefon Diggs, Kyle Rudolph, Adam Thielen, etc. Diggs and Thielen should only be considered as WR3 or WR4 plays, while Rudolph remains a low-end TE1 for his ability in the red zone. The Buccaneers DST is also a favorable unit to play against Keenum.
Demaryius Thomas - WR - Denver Broncos
Denver Broncos WR Demaryius Thomas (hamstring) fully participated in practice and is not on the injury report for Week 3.
Huddle Up: Thomas is off to a solid start this season with 11 catches and 138 yards in two games. He will continue to be a focal point in the passing game for Denver and should be considered a No. 2 fantasy receiver in all leagues.