• Karlos Williams - RB
    Posted 10/6/15 10:01am ET

    Buffalo Bills RB Karlos Williams (concussion) sustained a concussion in Week 4, and his status is uncertain against the Tennessee Titans in Week 5.

    Huddle Up: The status of LeSean McCoy's hamstring becomes more important if his caddy Williams can't go. Boobie Dixon would be in line for the heaviest portion of the workload, with Cierre Wood chipping in as well.

  • LeSean McCoy - RB
    Posted 10/1/15 4:38pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) and WR Sammy Watkins (calf) will not play in Week 4 against the New York Giants.

    Huddle Up: That means RB Karlos Williams and WRs Percy Harvin and Robert Woods suddenly are more attractive fantasy options, especially the former, who has scored in all three games so far even with McCoy playing.

  • Sammy Watkins - WR
    Posted 9/30/15 1:57pm ET

    Buffalo Bills WR Sammy Watkins (calf) may not be able to play in Week 4 against the New York Giants, according to head coach Rex Ryan. Watkins is not practicing Wednesday, Sept. 30. 'Part of when he had the surgery, it takes away a little bit of your conditioning,' Ryan said. 'He has the pull in camp, misses time. Now he's coming back, and he's got something else. It's just one of those things.'

    Huddle Up: If he's out, it'll continue a season of fantasy frustration so far for Watkins' fantasy owners as he was shut out in Week 1 and then caught only one pass for 39 yards last week following his 6-60-1 showing in between. Watkins played all 16 games as a rookie a year ago but his performance was clearly limited by injury issues down the stretch, and he's beginning to develop an injury-risk reputation.

  • Sammy Watkins - WR
    Posted 9/30/15 11:13pm ET

    Updating a previous report, Buffalo Bills WR Sammy Watkins (calf) probably will not be able to play in the Week 4 game against New York Giants, according to head coach Rex Ryan.

    Huddle Up: Watkins can safely be ruled out by fantasy owners. That means added targets for Percy Harvin, Robert Woods and tight end Charles Clay. Harvin will be the biggest beneficiary with Watkins out.

  • LeSean McCoy - RB
    Posted 9/29/15 4:51pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) is unlikely to play in Week 4 against the New York Giants as he deals with his hamstring injury, according to sources.

    Huddle Up: Even if you're not a McCoy owner, make sure to put in a waiver claim this week for rookie Karlos Williams, who has shown a big-play ability in leading the Bills' in rushing (24-186) and finding the end zone in all three games so far.

  • Tyrod Taylor - QB
    Posted 9/29/15 10:43pm ET

    Buffalo Bills QB Tyrod Taylor is the only quarterback in the NFL who ranks in the top five in completion percentage (74.4 percent), yards per attempt (9.15) and touchdowns (7).

    Huddle Up: Many had pegged Taylor as a fantasy sleeper -- but it was based almost exclusively on his upside as a runner. His passing prowess, though, has been nothing short of a revelation, and it's why he's fantasy's fifth-ranked QB through three weeks.

  • Sammy Watkins - WR
    Posted 9/28/15 2:51pm ET

    Buffalo Bills WR Sammy Watkins (calf) was diagnosed with a mild calf strain and is listed as day-to-day, according to a source informed of the injury. However, head coach Rex Ryan said there's a chance that Watkins won't be able to play in Week 4 against the New York Giants. Watkins had only one catch for 39 yards in Week 3 before he was hurt.

    Huddle Up: If Watkins is out against the Giants, Percy Harvin, Robert Woods and tight end Charles Clay will see more targets. Watkins hasn't been a big part of the offense this year but quarterback Tyrod Taylor has still shined.

  • LeSean McCoy - RB
    Posted 9/24/15 12:59pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) is practicing Thursday, Sept. 24.

    Huddle Up: McCoy returned to work after being held out Wednesday and, at the moment, looks like he'll be good to go Sunday in Miami.

  • Matt Cassel - QB
    Posted 9/22/15 7:56pm ET

    Buffalo Bills QB Matt Cassel was acquired by the Dallas Cowboys on Tuesday, Sept. 22. Dallas acquired Cassel and Buffalo's 2017 seventh-round draft pick for Dallas' fifth in 2017, sources said.

    Huddle Up: The Cowboys wanted veteran insurance behind new starter Brandon Weeden, and the unproven Kellen Moore wasn't going to cut it. Moore, though, will be the No. 2 QB until Cassel gets up to speed on the offense.

  • LeSean McCoy - RB
    Posted 9/18/15 1:19pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) is running routes and doesn't appear limited early in practice Friday, Sept. 18. Backup Karlos Williams thinks McCoy will play while coach Rex Ryan said he remains a little concerned, and McCoy is officially listed as questionable for the Sunday, Sept. 20 game against the New England Patriots.

    Huddle Up: McCoy owners can be somewhat optimistic, but it looks as if we're headed toward a Sunday-morning game time decision. And even if he does play, how close to 100 percent McCoy will be or how the Bills' RB workload will shake out are whole other questions entirely.

  • LeSean McCoy - RB
    Posted 9/17/15 3:32pm ET

    Updating a previous report, Buffalo Bills RB LeSean McCoy (hamstring) was limited in practice Thursday, Sept. 17. Head coach Rex Ryan said McCoy's hamstring is tight, and he's hoping he's ready to play in Week 2 against the New England Patriots. If he's unable to play, RB Karlos Williams would be the Bills starting running back.

    Huddle Up: McCoy had a team-high 20 touches in Week 1 after the hammy issue kept him out for most of the preseason, but it sounds like things still remain tricky. Let's see if the prognosis gets any brighter Friday.

  • Bryce Brown - RB
    Posted 9/15/15 5:00pm ET

    Buffalo Bills RB Bryce Brown was released Tuesday, Sept. 15.

    Huddle Up: This provides a little more clarity to the Buffalo backfield, and it looks like rookie Karlos Williams is the LeSean McCoy handcuff and not veteran Boobie Dixon after the former's impressive 6-55-1 debut Sunday.

  • LeSean McCoy - RB
    Posted 9/11/15 3:26pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) is listed as probable for Week 1 against the Indianapolis Colts.

    Huddle Up: Despite entering the week with dire opening-game outlook, the former Philly RB has been able to put in full practices all week and is a solid RB1 play against the visiting Colts.

  • Charles Clay - TE
    Posted 9/11/15 6:42pm ET

    Buffalo Bills TE Charles Clay (knee) fully participated in practice Friday, Sept. 11, and is listed as probable for Week 1.

    Huddle Up: Clay will be good to go Sunday, but the whole Buffalo offense remains an enigma with a new coach, new personnel at every skill position and a veteran first-time starting QB. It might be best to see how the whole scheme comes together first before banking on anyone outside of LeSean McCoy and Sammy Watkins.

  • LeSean McCoy - RB
    Posted 9/9/15 3:47pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) was a full participant in practice Wednesday, Sept. 9 but said he doesn't think he'll be 100 percent for the season opener Sunday. Earlier, Bills coach Rex Ryan said McCoy may not be limited much, and he joked that McCoy's pitch count would be '100.'

    Huddle Up: Great news overall for McCoy owners as the situation was definitely a lot bleaker even a day ago, and if he's playing, chances are you don't have a better RB option on your roster.

  • Sammy Watkins - WR
    Posted 9/8/15 10:05pm ET

    Buffalo Bills WR Sammy Watkins (gluteus) said he believes he's ready to play in Week 1 against the Indianapolis Colts. 'For the most part it's just about getting mentally and physically prepared for this game and enduring some physical battles,' Watkins said. 'So I think I'm in shape. I'm ready to go.'

    Huddle Up: Watkins remains the Bills' true No. 1 WR, but while Tyrod Taylor's ascension to the starting-QB role should boost the Buffalo ground game, it's probably not the best of news for Watkins and Co. That said, Watkins projects as a low-end WR2 this season.

  • Karlos Williams - RB
    Posted 9/5/15 12:02am ET

    Buffalo Bills RB Karlos Williams (undisclosed) said he believes he will be able to play in Week 1 after missing time in the preseason because of an undisclosed procedure. Williams believes he will play on special teams and hopes to be part of the running back rotation.

    Huddle Up: With LeSean McCoy uncertain for Week 1, Williams would be part of a running back rotation with Boobie Dixon and Bryce Brown if healthy. Williams has a good matchup against the Colts but a rookie coming off an injury and splitting time makes for a dicey fantasy play.

  • Matt Cassel - QB
    Posted 9/5/15 3:36pm ET

    Buffalo Bills QB Matt Cassel was released Saturday, Sept. 5.

    Huddle Up: Cassel thought he was safe but that's not the case. Cassel loses out to Tyrod Taylor and E.J. Manuel. He'll try to catch on with another team as a backup.

  • Leodis McKelvin - CB
    Posted 9/4/15 3:56pm ET

    Buffalo Bills CB Leodis McKelvin (ankle) was placed on the Non-Football Injury list Friday, Sept. 4, and he will miss the first six games of the season.

    Huddle Up: IDP alert and a blow to the back end of the Bills' defense with McKelvin hurt again after missing six games last season.

  • LeSean McCoy - RB
    Posted 9/4/15 6:46pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) said he did not do much running or cutting during practice Friday, Sept. 4. McCoy does not know if he will be able to play in Week 1.

    Huddle Up: We're basically down to a week to go now, and it's not looking especially promising for McCoy, who was injured in practice Aug. 18. If McCoy can't go, Anthony Dixon or Bryce Brown likely will get the start.

  • Matt Cassel - QB
    Posted 9/4/15 9:54pm ET

    Buffalo Bills QB Matt Cassel said the team has indicated that they will hold three quarterbacks on the roster heading into the regular season. Head coach Rex Ryan was vague on whether he will keep three quarterbacks. Cassel played in only four series in the preseason.

    Huddle Up: Tyrod Taylor will begin the season as the Bills' starter. If Buffalo does keep three quarterbacks, it's anyone's guess who will come in should Taylor struggle or get injured. The smart money is on E.J. Manuel.

  • LeSean McCoy - RB
    Posted 9/4/15 9:54pm ET

    Buffalo Bills RB LeSean McCoy (hamstring) could receive a limited amount of snaps if he plays in Week 1 because of his injury, and the team could hold him out if he is not 100% healthy, according to a source. McCoy said he hopes to be able to play in the game.

    Huddle Up: Rookie Karlos Williams said he'll be ready for the opener, so expect him and Bryce Brown to be part of a rotation if McCoy can't go. The Bills' running back rotation will be a mystery right up until kickoff.

  • Marcus Thigpen - WR
    Posted 9/3/15 8:40am ET

    Buffalo Bills WR Marcus Thigpen was considered outside looking in at the start of training camp and the preseason, but he has proved his worth in the return game and is making it difficult on the team to cut him from the 53-man roster.

    Huddle Up: Thigpen's return skills could earn him a spot at the end of the Buffalo receiver rotation and push the likes of Dezmin Lewis and Andre Davis onto the practice squad or out the door. However, given the Bills' quarterback situation and Rex Ryan's preference for the ground game Buffalo's WR5 doesn't bring much fantasy value to the table.

  • Matt Cassel - QB
    Posted 9/2/15 10:02am ET

    Buffalo Bills QB Matt Cassel could be cut by the team, as they are internally discussing the option.

    Huddle Up: Rex Ryan is all in on Tyrod Taylor, and the club is only a couple years removed from investing a first-round pick in EJ Manuel so he's not going anywhere, either. The veteran Cassel could catch on as a clipboard holder/insurance policy elsewhere, and the Bills may give him that opportunity sooner rather than later.

  • LeSean McCoy - RB
    Posted 9/2/15 1:51pm ET

    Updating an earlier report, Buffalo Bills RB LeSean McCoy (hamstring) may not be in great 'football shape' once Week 1 rolls around, according to a source. He's not at full speed in practice but is doing rehab work including light footwork, agility and cardio conditioning. A source told ESPN's Josina Anderson McCoy's MRI showed, what was described internally as, a 'small tear,' adding: 'They say it tore in a spot where it couldn't have been any better for us. It tore in a spot that is kind of high up, surrounded by stronger muscles in the glutes and things like that.'

    Huddle Up: McCoy only logged seven preseason touches before injuring his hammy in practice, and veteran Anthony Dixon appears to be the next in line on the RB depth chart with Bryce Brown and fifth-round pick Karlos Williams also likely to be mixed in if McCoy misses a game. Certainly stay tuned ...

  • Fred Jackson - RB
    Posted 9/1/15 9:17am ET

    Free-agent RB Fred Jackson (Bills) is meeting with the Seattle Seahawks Tuesday, Sept. 1, and both sides expect a deal to get done.

    Huddle Up: The veteran Jackson goes to a Super Bowl contender; the Seahawks get a capable backup to Marshawn Lynch. It's a win-win situation.

  • Tyrod Taylor - QB
    Posted 9/1/15 6:37pm ET

    Buffalo Bills QB Tyrod Taylor has the support of his teammates after he was named the team's starting quarterback heading into Week 1. 'He's going to be tremendous for this team,' said WR Percy Harvin . 'With the weapons that we already have I think teams have to worry about that, but now they have to worry about his legs too with the 4.4 speed he puts on the field I think is going to be tremendously dangerous for opponents to prepare for us.' Taylor has speed, but he also impressed this preseason with his accuracy from the pocket. He was 19-for-23 for 187 yards and a passer rating of 100.5 when he started with the first-team.

    Huddle Up: Taylor's presence figures to be a boon for LeSean McCoy as defenses will have to respect the QB's legs, but Taylor himself doesn't really hold any fantasy relevance outside of super-deep or two-QB leagues.

  • Tyrod Taylor - QB
    Posted 8/31/15 1:17pm ET

    Buffalo Bills QB Tyrod Taylor was named the starting quarterback Monday, Aug. 31, over QB Matt Cassel an QB EJ Manuel.

    Huddle Up: Despite not starting the third preseason game, Taylor was considered the favorite and got the job. Taylor has only started one NFL game in his career but brings some fantasy upside because of his running ability. Remember, Tim Tebow was a productive fantasy quarterback. Taylor is a QB2 with a chance to rise as the year goes on.

  • Percy Harvin - WR
    Posted 8/31/15 10:33pm ET

    Buffalo Bills WR Percy Harvin (hip) participated in team drills during practice Monday, Aug. 31.

    Huddle Up: The oft-injured Harvin has been dealing with a hip issue all preseason that has kept him out of the games, but he just may be getting healthy at the right time.

  • Mario Williams - DE
    Posted 8/31/15 11:54pm ET

    Buffalo Bills DE Mario Williams did not participate in practice Monday, Aug. 31, because of a calf injury.

    Huddle Up: Williams has played in all three preseason contests to date, and there's been no indication the calf issue is anything too serious -- so plan on Williams having basically two weeks to get ready for the Week 1 opener against Andrew Luck and the Colts.

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